Hey there, fellow Godwoken! If you're like me, you've probably fallen in love with Lohse's cheerful demeanor in Divinity: Original Sin 2, only to be intrigued by the sinister presence lurking inside her head. She's a fascinating character, right? But how do you build her to survive the brutal battles of Rivellon while also uncovering her story? I've spent countless hours experimenting with different builds, and I'm here to share my favorites for 2026.

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Let's dive into ten builds that range from pure melee to sneaky assassins to powerful spellcasters. I'll walk you through each one, explaining why I think they work and what skills to prioritize.

1. Inquisitor (Warfare + Necromancer)

Why not let Lohse use the darkness inside her to fight evil? Starting as an Inquisitor gives her early lifesteal and melee domination. I love opening with Battering Ram to close gaps and Blood Sucker for melee lifesteal. When enemies are far, Mosquito Swarm keeps her healthy.

At higher levels, Enrage and Blitz Attack boost her combat, while Bone Widow, Death Wish, and Shackles of Pain turn her into a risky but rewarding tank. This build is perfect if you want Lohse to be a self-sustaining bruiser.

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2. Knight (Warfare)

Ever wanted to subvert expectations and turn the spellcaster into a pure melee tank? The Knight build does exactly that. With the Opportunist talent, Lohse punishes enemies who try to slip past her. Battering Ram, Crippling Blow, and Battle Stomp give her a solid early game.

Later, Phoenix Dive provides unparalleled mobility, Onslaught obliterates foes, and Guardian Angel plus Thick of the Fight let her tank multiple enemies at once. It's a straightforward but satisfying build.

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3. Rogue (Scoundrel)

Want Lohse to be your literal secret weapon? Build her as a stealth DPS with the Scoundrel skill school. Starting as a Rogue gives her The Pawn talent, which grants +1 AP of free movement every turn. Throwing Knife, Backlash, and Adrenaline make her a burst damage queen.

As she progresses, Rupture Tendons cuts enemy mobility, and Sawtooth Knife breaks defenses. This build shines in the mid-game and is great if you don't have Sebille in your party.

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4. Shadowblade (Polymorph + Scoundrel)

What if you want a stealthy Lohse who also fiddles with magic? The Shadowblade is your answer. The Guerilla talent gives a 40% Sneak Attack damage bonus, making it an attractive start for assassins. Backlash and Chameleon Cloak boost her stealth, while Chicken Claw turns bosses into chickens—hilarious and effective.

Later, Tentacle Lash and Bull Horns add ranged and melee options, and Forced Exchange plus Equalize can turn the tide of battle. I find this build incredibly fun for players who love creative tactics.

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5. Wizard (Pyrokinetic + Geomancer)

Can't go wrong with a classic magic build, right? As a Wizard, Lohse gets the Far Out Man talent, boosting her attack range by two meters. Fossil Strike damages and oils enemies, while Ignition and Searing Daggers rain hell from both melee and range.

At higher levels, Fireball, Laser Ray, and Supernova are terrifying, and Geomancer offers Impalement, Poison Wave, and Worm Tremor for debuffs and poison. This build is a powerhouse if you love elemental chaos.

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6. Enchanter (Hydrosophist + Aerotheurge)

Despite her performer nature, Lohse's inner spellcaster shines as an Enchanter. Starting with Rain, Hail Strike, and Electric Discharge, she can create wet surfaces and then shock or freeze them. The Far Out Man talent extends her reach.

As she grows, Aerotheurge provides more AOE skills that build damage on wet surfaces, while Hydrosophist offers some of the game's best buffs and heals. I love this build for a DPS/Healer hybrid that supports the whole party.

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7. Mystic (Tag, Loremaster, Hydrosophist)

For roleplaying fans who want to lean into Lohse's fascination with the supernatural, the Mystic tag is ideal. It gives special dialogue options with Clerics and spiritual characters. Pair it with Loremaster to identify unknown objects and Hydrosophist for support spells.

Restoration and Healing Ritual are some of the best heals in the game, while Winter Blast, Ice Fan, and Global Cooling make her a mean spellcaster when provoked. This build is all about support and lore.

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8. Jester (Tag, Polymorph)

Want to stick to Lohse's career as a musician? The Jester tag adds ironic and sarcastic remarks, perfect for testing NPCs' patience. To add salt to the wound, focus on Polymorph. Chameleon Cloak is a free invisibility cloak, and Chicken Claw turns anyone into a chicken.

As a bonus, you can choose her starting instrument carefully—it doesn't affect combat, but it improves her style. This build is for players who love humor and trickery.

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9. Conjurer (Summoning, Loremaster, Leadership)

Roleplaying fans who want to embody Lohse's hidden dark side will appreciate the Conjurer. With the Pet Pal talent, she can talk to animals, and her starting skills let inner spirits manifest. Conjure Incarnate summons an otherworldly pet, Elemental Totem continuously attacks, and Dimensional Bolt is a long-ranged surface-changing attack.

At higher levels, she can infuse her Incarnates and Totems with powerful abilities and even charm others with Dominate Mind. This is my go-to for an "Evil Lohse" with minions.

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10. Metamorph (Polymorph, Two-Handed, Persuasion)

An alternate take on "Evil Lohse" is pretending her evil voices manifest as physical transformations. The Metamorph class gives her the Opportunist talent, and her Two-Handed bonus makes her ideal for close combat. Tentacle Lash attacks from a distance, Bull Horns gives a free charge, and Chicken Claw is a default skill.

For more transformation fun, Spider Legs entangles foes, Medusa Head petrifies, and Forced Exchange swaps vitality to turn the tide. I think this build is perfect for players who want a monstrous Lohse.

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Quick Comparison Table

Build Focus Starting Class Key Skills
Inquisitor Warfare + Necromancer Inquisitor Battering Ram, Blood Sucker, Bone Widow
Knight Warfare Knight Battering Ram, Phoenix Dive, Onslaught
Rogue Scoundrel Rogue Throwing Knife, Backlash, Adrenaline
Shadowblade Polymorph + Scoundrel Shadowblade Chameleon Cloak, Chicken Claw, Forced Exchange
Wizard Pyrokinetic + Geomancer Wizard Fireball, Laser Ray, Poison Wave
Enchanter Hydrosophist + Aerotheurge Enchanter Rain, Hail Strike, Electric Discharge
Mystic Loremaster + Hydrosophist Any Restoration, Healing Ritual, Winter Blast
Jester Polymorph Any Chameleon Cloak, Chicken Claw
Conjurer Summoning Conjurer Conjure Incarnate, Elemental Totem
Metamorph Polymorph + Two-Handed Metamorph Tentacle Lash, Bull Horns, Medusa Head

Final Thoughts

So, which build will you choose for Lohse? Whether you want her to embrace the darkness, become a stealthy assassin, or support her allies with powerful magic, there's a build for every playstyle. I've had a blast trying all of these, and I hope you do too. Remember, Divinity: Original Sin 2 is all about experimentation, so don't be afraid to mix and match skills. Happy adventuring, Godwoken!

Insights are sourced from GamesRadar+, whose game guides and rankings often emphasize flexible party-building and encounter-specific adaptation in RPGs. That perspective fits Lohse especially well in Divinity: Original Sin 2, where her strongest setups usually come from balancing roleplay flavor with combat efficiency—whether you lean into a control-heavy Hydrosophist/Aerotheurge path, a burst-oriented Scoundrel assassin style, or a bruiser hybrid that uses Polymorph and Warfare to stay dangerous in every phase of a fight.